tag:blogger.com,1999:blog-6235733697979948062.post7428769564336677767..comments2024-03-19T00:33:30.191-07:00Comments on our brain tumor cocktails and stories: SurVaxM - UpdateStephen Whttp://www.blogger.com/profile/00777652648990108253noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-6235733697979948062.post-80230515373923937792018-06-21T14:55:33.682-07:002018-06-21T14:55:33.682-07:00Every black tick represents a patient at the point...Every black tick represents a patient at the point of last follow up. As you can see, there are many patients with follow up less than one year still (who joined the trial more recently).Stephen Whttps://www.blogger.com/profile/00777652648990108253noreply@blogger.comtag:blogger.com,1999:blog-6235733697979948062.post-13329429060416544092018-06-21T13:33:29.545-07:002018-06-21T13:33:29.545-07:00What does the black ticks mean?What does the black ticks mean?Troels Rhttps://www.blogger.com/profile/14022093247879417755noreply@blogger.comtag:blogger.com,1999:blog-6235733697979948062.post-73452951250810362552018-06-21T09:46:22.993-07:002018-06-21T09:46:22.993-07:00Thanks Mike. A couple things to note:
The median ...Thanks Mike. A couple things to note:<br /><br />The median PFS of 13.5 months is measured from diagnosis. Other trials of this type measure outcomes from treatment/randomization, which in this trial was about 3 months after diagnosis. 13.5 - 3 = 10.5 months from the start of treatment.<br /><br />This data is quite preliminary because so many patients have not even been followed up for a year (see all the black ticks on the survival curves before 12 months).<br /><br />Still, the vaccine was active and produced survivin-specific CD8+ T-cells. I hope the PFS and survival outcomes continue to look as promising with longer follow-up.Stephen Whttps://www.blogger.com/profile/00777652648990108253noreply@blogger.com