Hi, I would like to know if Radio and Chemotherapy could generate Osteonecrosis.
Recently my niece received the diagnosis of Osteonecrosis (after a MR), she has
had pain located in her hip, and a little limp. Now we are consulting the best
way to heal, but we have doubt about if it’s advisable to stop de chemotherapy.
My niece after two operation (she has a GBM no methilated) she was treated
at the same time with radiotherapy and chemotherapy for 6 week, and right
now she is taking the 3rd cyclo of six (temodar 5x23 about 360 daily).
I’m looking forward for your answer.
Sincerely, Jose Mª
My husband had osteonecrosis at the site of his craniotomy. He had an infection under the bone flap after the initial surgery and had the have a second surgery where they removed the bone flap. A year later, after radiation and a year of treatments (temodar, then CCNU, then CPT-11 and carboplatin) he developed recurrent infections at the site. After many months, it was determined that osteonecrosis was present and was a primary contributor to the recurrent infection. Radiation was believed to be a contributor to it developing.
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