Update on phase 2 trial of valproic acid + standard chemoradiation for nd GBM

As reported several years ago, median survival in this trial of high dose valproic acid (Depakote) in combination with chemoradiation was 29.6 months.  This study describes 6 patients who survived over three years (median survival over 6 years for these 6 patients).  Only 1 out of 4 evaluated tumors carried the IDH1 mutation.

https://academic.oup.com/nop/advance-article/doi/10.1093/nop/npy009/4971616  (abstract only)


http://sci-hub.tw/https://academic.oup.com/nop/advance-article/doi/10.1093/nop/npy009/4971616

Note the above link takes you to a PDF download at sci-hub.  If this link fails to work in the future, check wikipedia for the current active locations of sci-hub, and swap out the ".tw" in the URL with something else.  This is technically pirating, but most of us here would agree that fighting a brain tumor calls for such measures.