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Showing posts with label statins. Show all posts
Showing posts with label statins. Show all posts
Tuesday, 13 February 2018

IDH1 R132H Mutation Enhances Cell Migration by Activating AKT-mTOR Signaling Pathway, but Sensitizes Cells to 5-FU Treatment as NADPH and GSH Are Reduced

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215606/#!po=0.595238 Has this been shared here yet? The AKT/mTor pathway is related to gluc...
2 comments:
Thursday, 8 February 2018

Do statins, ACE inhibitors or sartans improve outcome in primary glioblastoma?

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This is a new paper (click here for abstract) brought to us by some of the same authors who earlier produced: Does Valproic Acid or Levet...
Tuesday, 25 July 2017

Simvastatin positive evidence in an orthotopic GBM model

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The study is called  MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells This study constitutes in my view...
Thursday, 27 April 2017

GBM suck up cholesterol

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http://www.cell.com/cancer-cell/pdf/S1535-6108(16)30443-3.pdf Any thoughts/further info on this method?
11 comments:
Saturday, 22 October 2016

An argument against statin use for GBM

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A new study by a joint team from UCLA, UCSD etc. has important implications for the use of statins as a repurposed GBM therapy.   The study ...
6 comments:
Tuesday, 27 October 2015

Ibuprofen and Care Oncology

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Hi all, My Mum was sadly diagnosed with Glioblastoma in July. I have been meaning to post her cocktail here and get involved in this blog,...
13 comments:
Wednesday, 2 September 2015

What about statins?

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So my brothers tumor has high PKB/AKT . As far as I understood Ben states in his pdf that lovastatin can suppress the PKB/AKT. I noticed tha...
5 comments: