Saw an article in Neurology about the effect of high fat meals on CBD uptake. Showed significantly more bio-availability with high fat meals. Roughly 4x increase with high fat meal, 2x increase with low fat meal, vs a fasted state.
Useful info for those using CBD for treatment. Note this paper did not investigate THC which will behave differently.
https://onlinelibrary.wiley.com/doi/abs/10.1111/epi.16419
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