As reported several years ago, median survival in this trial of high dose valproic acid (Depakote) in combination with chemoradiation was 29.6 months. This study describes 6 patients who survived over three years (median survival over 6 years for these 6 patients). Only 1 out of 4 evaluated tumors carried the IDH1 mutation.
https://academic.oup.com/nop/advance-article/doi/10.1093/nop/npy009/4971616 (abstract only)
http://sci-hub.tw/https://academic.oup.com/nop/advance-article/doi/10.1093/nop/npy009/4971616
Note the above link takes you to a PDF download at sci-hub. If this link fails to work in the future, check wikipedia for the current active locations of sci-hub, and swap out the ".tw" in the URL with something else. This is technically pirating, but most of us here would agree that fighting a brain tumor calls for such measures.
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