It would seem one has to be in a clinical trial to get ONC201: https://clinicaltrials.gov/ct2/results?term=ONC201&Search=Search There's a published report of an early-phase human study: http://mct.aacrjournals.org/content/14/12_Supplement_2/C137.short
In a mouse GBM study, ONC201 on its own wasn't very effective, but was effective combined with an experimental drug that inhibits Bcl-2 and Bcl-xl (both are anti-apoptotic, or cell survival proteins).
It would seem one has to be in a clinical trial to get ONC201:
ReplyDeletehttps://clinicaltrials.gov/ct2/results?term=ONC201&Search=Search
There's a published report of an early-phase human study:
http://mct.aacrjournals.org/content/14/12_Supplement_2/C137.short
ONC201 is a dual kinase inhibitor of Akt and ERK.
ReplyDeletehttp://www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=757339
In a mouse GBM study, ONC201 on its own wasn't very effective, but was effective combined with an experimental drug that inhibits Bcl-2 and Bcl-xl (both are anti-apoptotic, or cell survival proteins).
http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=5505&pubmed-linkout=1
The doctor said that it is possible to buy it in a german pharmacy. I am wondering if it is worth purchasing and about any side effects of it.
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