Saturday, 5 March 2016

Taurine supplementation slows tumor growth in a nude mouse GBM model

This is not the most accurate model for human GBM (U87 GBM cell line which is going on 50 years old; subcutaneous rather than orthotopic tumor implantation), but still interesting, showing that taurine supplementation slows tumor growth in the mice by antagonizing hypotaurine.

Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling

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