Hi all
Wondering if any1 could help me.
My dad's pathology report stats that he has over expressed BCAT1 and is idh1 wild type.
I have been searching trying to find something that may be able to block this aggressive amino acid.
I have only found one paper paper to suggest that a drug may help it is an anti seizer med called gabapentin, has any1 took or used this before ?
BCAT1 is the reason wild type idh1 are more aggressive.
Also I was wondering if anyone knows of any know ways of blocking glutamate? As this is what fuels these things?
http://www.patentsencyclopedia.com/app/20150374800
Many thanks all
Thanks for pointing out this use of gabapentin Dayle. I'm going to read up on it.
ReplyDeleteAnd I'll upload this study to the Library:
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.
http://www.ncbi.nlm.nih.gov/pubmed/23793099
Hi Stephen
ReplyDeleteThanks for the reply
That would be great if you could have a read and tell me what you think
I'm not very good at translating these papers into English :)
Do you know of any other methods or coukd you tell me the dosage that a human would need to take ?
Thanks for all your hard work mate