"This review provides an overview of the clinical literature to support a central hypothesis: that all GBM patients have tumor regions with an intact BBB, and cure for GBM will only be possible if these regions of tumor are adequately treated"
Abstract here, and again I can email the full study if anyone would like a copy.
Key quotes below:
Combined with the surgical experience, these data support our central contention that all GBM have a clinically significant tumor burden ‘protected’ by an intact BBB.
Accepting the importance of drug distribution across an intact BBB into brain is a critical first step in developing effective therapies for GBM and must be a key consideration in any clinical trial design for newly diagnosed or recurrent GBM.
I am interested. Will you upload it to BT library? (:
ReplyDeleteYes I will certainly upload it to the libarary now. Not sure why I didn't think of that. Thanks for the reminder.
DeleteUploaded to a new folder in the library (Blood-Brain Barrier in glioma)
DeleteAlso interested!
ReplyDeleteTone