Thursday, 30 July 2015

Cimetidine and Lansoprazole?

Hi all,

When perusing various cocktails posted on the groups I have noticed some people take Cimetidine, some take Lansoprazole (or Omeprazole), but no one seems to take both.  They seem to act in different ways (although treating similar systems for those using them for their intended purpose).  Is there a contraindication for using both?

Thank you!


  1. I'm not aware of any contraindication for using both cimetidine and a proton pump inhibitor, however this may of course lead to an increase in stomach pH and interfere with the absorption of drugs such as itraconazole, which require a lower pH for optimal absorption.

  2. We use both, but of course wonder how it is affecting the other drugs.

  3. My brother is using omeprazole and cimetidine for a few months without any problem. I am not sure what dosages because his wife is giving him drugs.