Tuesday, 25 July 2017

ONC 201 or Avastin?

Stephen and all,
We are trying to decide between treating our son (recurrent glioma, H3 K27 mutant, mutations in ASXL 1 and PIK3CA among others) with Avastin +Irotican  or the new ONC201 trial. We tend to think that ONC201 is a better option. What do you think? Thanks!
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4 comments:

  1. Stephen W25 July 2017 at 11:14

    Given his tumor has the H3 K27M mutation, my vote would be with ONC201.

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    1. Olga25 July 2017 at 12:24

      Thank you so much, yet again , Stephen! that's what we will do

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  2. SVG26 July 2017 at 06:15

    Question is: what is the age. I am not sure if pediatric doses are known. Otherwise see this publication where they mention one adult with histone mutation: the paper is free available: http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=17837&pubmed-linkout=1.

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    1. Olga26 July 2017 at 22:13

      Thanks! They actually said it will be adult dose

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