New study called Influence of metformin, sodium dichloroacetate and their combination on the hematological and biochemical blood parameters of rats with gliomas C6 published in Experimental Oncology.
https://www.ncbi.nlm.nih.gov/pubmed/30284997 (pubmed abstract)
http://exp-oncology.com.ua/wp/wp-content/uploads/2018/10/2507_01.pdf?upload= (PDF download)
"The administration of DCA did not significantly affect the life span
of rats with C6 glioma"
Average lifespan of rats was increased by 19% with metformin alone
Combination treatment with metformin and DCA increased average lifespan of rats by 50%
"the expressed antitumor effect of combination therapy with DCA and MTF [metformin] was associated with a decrease (p < 0.05) in glucose and lactate levels in blood plasma of rats with C6 glioma by 10% and 41.4%, respectively, compared to tumor control."
"Analysis of blood parameters showed that the growth of C6 glioma was accompanied by the development of leukopenia, anemia and thrombocytopenia."
"MTF [metformin] alone and in combination with DCA positively influenced the number of white blood cells and caused complete thrombocytopenia correction, increasing platelet count by more than 200%"
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