Sunday, 30 October 2016

Memantine and Radiation

Dear all:

This is to let you know that Memantine (Nameda, an anti-Alzheimer drug) can be used to prevent radiation-induced neurocognitive decline to a certain extent. My sister's radiation oncologist recommends it, it is apparently routinely prescribed for children undergoing brain radiation.
Patients usually take it a few days before radiation, during treatment, and for six months post-treatments. My sister's side effects so far have been headache, body ache, tiredness, and nausea.
But it might be worthwhile to ask for it.
Wishing you all the best,


  1. Thanks Meer, there has also been animal studies showing memantine can slow tumor growth in glutamate-secreting tumors.

    Memantine is also included in a GBM trial at MD Anderson

  2. Thank you Stephen for the info.

    Is there a way to know whether a glioma secretes glutamate?