Tuesday, 6 September 2016

Marizomib

Stephen and others

Anyone familiar with this drug?  Looks like it is in phase 1 trials, but on the Inspire board, someone was given Marizomib.  Does not sound like this was part of a clinical trial.  But this is a guess.

4 comments:

  1. I've seen studies on it. It's a proteasome inhibitor like bortezomib but apparently can cross the blood-brain barrier, unlike bortezomib.

    Wikipedia page:
    https://en.wikipedia.org/wiki/Salinosporamide_A

    Clinical trial:
    https://clinicaltrials.gov/ct2/show/NCT02330562

    The person on Inspire must either be in a clinical trial or got it on Compassionate Use. It isn't FDA approved yet.

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  2. My husband is doing the clinical trial right now... He gets his 2nd infusion tomorrow. Supposedly has had good success with recurring tumors so now they are trying it out for newly diagnosed.

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  4. HI Ester, can you comment on your husband's progress with marizomib? Thank you!

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