Study abstract here
I haven't read it yet, but already uploaded it to the Brain Tumor Library (Folder 1 human studies -> metformin)
From the abstract: "Interestingly, diabetic patients with metformin therapy demonstrated prolonged progression-free intervals."
I will probably summarize the findings on Astrocytoma Options soon.
The title of this article would lead one to believe Metformin leads to tumor progression.
ReplyDeleteUse of metformin and survival of patients with high-grade glioma.
ReplyDeletehttps://www.ncbi.nlm.nih.gov/pubmed/30091464
I think study included diabetic patients (which isn't mentioned in title). All the sci-hub links I have are down at the moment, so I can't check.
I was able to download this using sci-hub
Deletehttp://sci-hub.tw/https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.31783
This study was looking at a subgroup of 177 brain tumor patients who also had diabetes. 55 of them were on metformin and some were on other diabetes drugs.