ICT-107 vs. DC Vaccine trial selection

Thank you Stephen for setting me up on this site.

We are evaluating clinical trials to select one for my mother's GBM treatment. She has not yet started on radiation and Tamodar after the surgery. 

Does anyone on this forum have experience with ICT-107 vaccine (randomized with 50% placebo) or DC Vaccine (phase 1) or stem cell based protocol (personalized by UCSF)?  We have to choose one of these three this week itself as it's bee 4 week since her surgery and we are running out of time. Any insights or pointers to help select one would be highly appreciated. 

1)

https://www.clinicaltrials.gov/ct2/show/NCT02546102?term=NCT02546102&rank=1

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

2)

https://clinicaltrials.gov/ct2/show/NCT02010606

Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma

3)

An ex USCF doctor has offered to work with us on developing cell based high throughput cancer stem cell protocol. 

DC/NDV + TTF + maintenance TMZ....thoughts?

Hi all,

I'm 54 from Scotland, diagnosed in August with over 90% resection and am on my last stretch of radio/chemo before starting TMZ 5/28 for 6 months in December.

I'm currently in the position of deciding if i should start TTF therapy alongside maintenance, undergo DC&NDV vaccine at IOZK with maintenance, or embark on all three at once?

Any thoughts would be very much appreciated as i hear evidence for both  TTF and DC treatments working well with TMZ, i just don't know if it would be wise to combine them all. If that is the case, which would be more 'worth' it? If TTF doesn't work well with dexamethasone due to its immunosuppressive effects would it be better to support the immune system with the DC vax first?

Thank you for any thoughts on this matter, i aim to join you all and get my cocktail up soon!

Mark

ICT-107

Stephen and others

Phase 1 trials of ICT-107 looked very promising and I know phase 2 trials were started a few years back.  Any updates on how this is progressing?

Mike