Curcumin rescues mice with GL261 mouse glioma syngrafts

The blue line represents survival of mice treated intranasally with an experimental curcumin-antibody conjugate.  The red line represents mice injected intraperitoneally with 100 mg/kg curcumin in the form of Meriva Curcumin phytosomes.  These treatments dramatically shifted the phenotype of microglia from a tumor-promoting M2 type to an anti-tumor M1 type.

from the study:

Curcumin Changes the Polarity of Tumor-Associated Microglia and Eliminates Glioblastoma

online August 20, 2016 in the International Journal of Cancer  

to be uploaded in the Brain Tumor Library, folder 2, Curcumin subfolder

MATIAS - cocktail profile

Hi everyone!

So, I guess I´ll be the first one publishing my cocktail here!  

I think it is very straightforward and easy to understand, so I´ll just clarify that the items in bold are actual drugs, while the other are -mostly- supplements.  About genistein, it´s in red because I think the dose might be low, so if anyone is taking it, I´ll like to hear your opinion.

I´ll like to add that, besides from the cocktail above, that I take everyday, I do the following activities, which are related to my GBM treatment:

• monthly 5-day TMZ cycle (going for my 13rd cycle, and pretending to go up to the 24th).
• 4 daily Perillyl alcohol inhalations (around 30-40 minutes each).
• go to the gym twice a week.
• do a massage occasionally.
• follow a quite rigorous, very low-carb diet.

I´ll add some information about my own case here:

• giant cell GBM
• surgery on May 5th, 2014
• 31-year-old when diagnosed (33-year-old now)
• radiation + TMZ (SOC).
• MGMT: positive.
• IDH1: negative.
• EGFR: positive (>90%,+++).
• supplement cocktail started right away, with curcumin (added other supplements along the way).
• drugs where added this year, progressively.

I´m looking forward to hearing what you guys and girls think about my cocktail, how it compares to yours and what else you do to fight GBM!

All the best,

Matias.