Questions about Celebrex and Tamoxifen

Hi,


I am new to agents of GBM. I have following questions


1) Is it necessary or beneficial to take Celebrex in the periods between chemotherapy(TMZ) cycles?


2) We also want to add Tamoxifen to my mother's cocktail list, But we are not sure if it will be effective.


3)One study article tells me that adding folic acid will be helpful to change MGMT from unmethylated status to methylated status, Is that correct?


It would be greatly appreciated if you could share your knowledge or information about these questions.


Stephen, Would you like to help me?


Best Regards
James Zhou

Drug related nutrient depletion-reason to take folate

Interesting article. Another reason to take folate
http://nutritionreview.org/2013/04/practical-guide-avoiding-drug-induced-nutrient-depletion/

What is folinic acid.

There is a clinical trial for gbm with folinic acid. I am wondering what is that. I guess it is not something widely available.