Sunday 26 June 2016

Nivo dosing

I am curious if anyone that is using Nivo (Opdivo) is on a different schedule than every two weeks.  My son is using Nivo outside of a clinical trial and is scheduled for infusion every two weeks at 240 mg for 4 months, then 480 mg monthly thereafter.  His NO said this is the way Nivo is now being used in clinical trials.  I have not heard of anyone else on this dosing schedule.
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3 comments:

  1. David26 June 2016 at 13:59

    Here is a clinical trial using that dosing strategy, maybe they suspect this is optimal from experience in lung cancer.

    Dosing with these drugs is something totally new, they were tested like old drugs and optimization strategies might help.

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  2. David26 June 2016 at 14:42

    https://clinicaltrials.gov/ct2/show/NCT02713867

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  3. Annie27 June 2016 at 10:54

    Dad gets infusions every 2 weeks. Not sure the dosage but I'll pay attention this Wednesday and let you know.

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